Key result
Intravenous immunoglobulin treatment in a 14-year-old with adenoviral myocarditis mimicking hypertrophic cardiomyopathy led to rapid resolution of ventricular hypertrophy.
Case Report (n=1)
Acute adenoviral myocarditis can present with transient concentric left ventricular hypertrophy mimicking hypertrophic cardiomyopathy, which resolves rapidly with appropriate treatment.
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Transient LVH may mimic HCM in acute myocarditis; case report leaves open IVIG role and generalizability.
A 14-year-old previously healthy female presented with chest pain and dyspnoea for 2 days in the setting of a recent upper respiratory infection. She had elevated inflammatory markers and troponin, resulting in the diagnosis of acute myocarditis. Transthoracic echocardiography demonstrated mild systolic dysfunction and a moderate pericardial effusion. Additionally, her echocardiogram showed concentric left ventricular hypertrophy raising concern for hypertrophic cardiomyopathy. She was treated with intravenous immunoglobulin. Serial echocardiograms revealed rapid resolution of her ventricular hypertrophy. Cardiac magnetic resonance confirmed the diagnosis of myocarditis.
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Aydin et al. (2023) conducted a case report in Adenoviral myocarditis mimicking hypertrophic cardiomyopathy (n=1). Intravenous immunoglobulin was evaluated on Resolution of ventricular hypertrophy. Intravenous immunoglobulin treatment in a 14-year-old with adenoviral myocarditis mimicking hypertrophic cardiomyopathy led to rapid resolution of ventricular hypertrophy.
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