Why the study?
Does elective stent implantation improve angiographic and clinical outcomes in patients with de novo lesions in saphenous vein grafts compared to balloon angioplasty?
Does elective stent implantation improve angiographic and clinical outcomes in patients with de novo lesions in saphenous vein grafts compared to balloon angioplasty?
Elective stent implantation in de novo saphenous vein graft lesions significantly reduces target vessel revascularization and improves event-free survival at 1 year compared to balloon angioplasty.
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Supports elective stenting in de novo SVG lesions; extends RCT evidence to graft interventions.
The aim of the study was to compare acute and long-term angiographic and clinical outcome of balloon angioplasty and elective stenting in de novo lesions in the body of a saphenous vein graft (SVG). A total of 150 patients, with de novo lesions in SVG, were randomly assigned to balloon angioplasty or elective Wiktor I stent implantation. The angiographic restenosis rate at 6-month follow-up was 32.8% in the balloon group and 19.1% in the stent group (P = 0.069). At 1-year follow-up, target vessel revascularization rate was 31.4% vs. 14.5% (P < 0.05), and event-free survival was 60.0% vs. 76.3% (P < 0.05) for the balloon and stent group, respectively. Elective stent implantation in de novo SVG lesions is associated with a significant lower target vessel revascularization rate and a significant higher event-free survival at 1-year follow-up as compared to balloon angioplasty.
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Hanekamp et al. (2003) studied this question.
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