Key result
A 31-year-old male with Brugada syndrome experienced recurrent syncope due to a 12-second sinus arrest after receiving a subcutaneous ICD, highlighting the importance of recognizing sinus node dysfunction in these patients.
Why the study?
Sinus node dysfunction is a less recognized conduction abnormality associated with Brugada syndrome that can alter clinical management.
Case Report (n=1)
Sinus node dysfunction is an important potential manifestation in Brugada syndrome that can cause syncope and should be considered when selecting device therapy, as S-ICDs cannot provide bradycardia pacing.
May warrant sinus node assessment before S-ICD in Brugada syncope; single case leaves open prevalence and device implications.
Brugada Syndrome is a rare arrhythmogenic entity that poses a risk of sudden cardiac death due to ventricular arrhythmias. Sinus node dysfunction is a less recognized and acknowledged conduction abnormality associated with Brugada syndrome, but nevertheless an important potential manifestation that can alter management. We present a case of a young patient who presented with syncope initially presumed to be secondary to a ventricular arrhythmia in the setting of newly diagnosed Brugada syndrome but was later found to have evidence of sinus node dysfunction. We review the relevant literature and discuss the management.
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Maya et al. (2021) conducted a case report in Brugada Syndrome and Sinus Node Dysfunction (n=1). Subcutaneous implantable cardioverter-defibrillator (S-ICD) was evaluated. A 31-year-old male with Brugada syndrome experienced recurrent syncope due to a 12-second sinus arrest after receiving a subcutaneous ICD, highlighting the importance of recognizing sinus node dysfunction in these patients.
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