Key result
An improved synthesis process for prasugrel hydrochloride achieved an overall yield of 58% and 99.9% purity while meeting all quality requirements.
The study details an optimized chemical synthesis for prasugrel hydrochloride, achieving high purity and yield.
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May support prasugrel supply consistency; leaves open clinical or economic translation.
An improved process for the synthesis of prasugrel hydrochloride with an overall yield of 58%, 99.9% purity, and meeting all other quality requirements is described.
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Sampath et al. (2012) studied this question. An improved synthesis process for prasugrel hydrochloride achieved an overall yield of 58% and 99.9% purity while meeting all quality requirements.
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