Key result
This analytical review summarizes modern data on the mechanisms, prevention, and treatment of diabetic cardiomyopathy, highlighting myocardial energy metabolism and replicative aging as therapeutic targets.
This review highlights myocardial energy metabolism and replicative aging as promising therapeutic targets for the prevention and treatment of diabetic cardiomyopathy.
Energy metabolism and replicative aging merit exploration as targets in diabetic cardiomyopathy; leaves open validation in prospective trials.
The article is an analytical review of clinical studies of structural and functional cardiac changes in patients with diabetes. Modern data on the mechanisms of the diabetic cardiomyopathy development, the options of its prevention and treatment are summarized. Particular attention is paid to the features of myocardial energy metabolism and replicative aging in this pathology, as promising targets for therapeutic interventions.
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Sorokina et al. (2019) conducted a review in diabetic cardiomyopathy. This analytical review summarizes modern data on the mechanisms, prevention, and treatment of diabetic cardiomyopathy, highlighting myocardial energy metabolism and replicative aging as therapeutic targets.
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