Key result
Higher maximum bite force was significantly associated with a lower risk of developing cardiovascular disease, with the highest quintile showing an 81% risk reduction compared to the lowest quintile (HR 0.19).
Why the study?
Decreased masticatory function is believed to be linked to cardiovascular disease through poor nutrition, but the association between maximum bite force and cardiovascular disease risk required investigation.
Does lower maximum bite force increase the risk of developing cardiovascular disease in urban residents?
Cohort (n=1,547)
No
Does lower maximum bite force increase the risk of developing cardiovascular disease in urban residents?
Lower maximum bite force is significantly associated with an increased risk of developing cardiovascular disease, particularly in women, suggesting it may serve as a novel risk marker.
Decreases in masticatory function are believed to be related to the development of cardiovascular disease (CVD) through inappropriate nutritional intake. This study focused on maximum bite force (MBF), which is an objective, quantitative index of masticatory function, and its association with the development of CVD (stroke and coronary heart disease) was investigated. The subjects were 1547 participants of the Suita study with no history of CVD who underwent medical and dental health examinations between June 2008 and June 2013. In addition to undergoing a basic physical examination at baseline, their MBF was measured. They subsequently underwent follow-up surveys for the development of CVD (mean follow-up, 3.5 years). The association between baseline MBF and the development of CVD was investigated by multivariate adjustment using a Cox proportional hazards model. CVD developed in 32 subjects during follow-up. The trend test showed a significant association between baseline MBF and CVD in a model that combined men and women. When analysed by sex, the trend test found a significant association between baseline MBF and CVD in women. Low MBF, which is an objective and quantitative index of masticatory function, may be a risk factor for the development of CVD.
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Hashimoto et al. (2021) conducted a cohort in Cardiovascular disease (n=1,547). Maximum bite force vs. Lowest quintile of maximum bite force was evaluated on Incidence of cardiovascular disease (stroke and coronary heart disease) (HR 0.19, 95% CI 0.04-0.96, p=0.03). Higher maximum bite force was significantly associated with a lower risk of developing cardiovascular disease, with the highest quintile showing an 81% risk reduction compared to the lowest quintile (HR 0.19).
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