Non-lithographic fabrication of a self-aligned nanopore SERS array with large-area hexagonal symmetry is achieved by Au deposition on an anodized aluminum oxide (AAO) template. Precise self-formation of plasmonic nanopore arrays with facile structural tunability allows control of the SERS response, and results in highly reproducible, uniform, and sensitive SERS with an enhancement factor of 107.
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Choi et al. (2010) studied this question.
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