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August 10, 2021European Heart Journal Acute Cardiovascular Care

Dissecting the epidemiology of aortic dissection

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Why the study?

Epidemiological data on acute aortic dissection remain scanty and actual incidence is hard to estimate due to diagnostic challenges and pre-hospital deaths.

Population

Patients with acute aortic dissection (AAD)

Design

Editorial

Key result

Acute aortic dissection has an estimated prevalence of 0.2% to 0.8% in autopsy series and an annual incidence of 2.5 to 7.2 cases per 100,000 in population-based studies.

Authors

VAVictor AboyansMBMarouane Boukhris

Discussion

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Member takes

Overview

Registry data likely underestimate incidence; leaves open accurate epidemiology until population studies routinely include out-of-hospital deaths.

Structured PICO

P
Population
Patients with acute aortic dissection (AAD)

Accurate epidemiological estimation of acute aortic dissection requires population-based studies that include out-of-hospital deaths, as registry data alone underestimates the true incidence.

Limitations

  • Actual incidence is hard to estimate because a significant proportion of patients die before medical contact, leading to low rates of autopsy confirmation and incomplete inclusion in registries.

Cite This Study

Aboyans et al. (2021) conducted an editorial in Acute aortic dissection. Acute aortic dissection has an estimated prevalence of 0.2% to 0.8% in autopsy series and an annual incidence of 2.5 to 7.2 cases per 100,000 in population-based studies.

synapsesocial.com/papers/6a98bfa005ccbca0e518e280https://doi.org/10.1093/ehjacc/zuab065
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acute aortic dissection (AAD) – a lethal disease: the epidemiology, pathophysiology and natural history2023 · 17 citations
  2. 2Aortic dissection: global epidemiology2022 · 33 citations
  3. 3Epidemiology of Acute Aortic Dissection in a General Population of 1.4 Million People in Japan ― Shiga Stroke and Heart Attack Registry ―2023 · 13 citations
  4. 4Incidence, risk factors, outcome and projected future burden of acute aortic dissection.2014 · 66 citations
  5. 5Aortic dissection: medical, interventional and surgical management2016 · 108 citations