Key result
In a mathematical model of Jeffrey blood flow, increasing the relative stenosis height reduced blood flow velocity, while an increased ratio of relaxation time expanded the dispersion function along the arterial wall.
Why the study?
The study aimed to analyze the impact of the ratio of relaxation time, slip velocity, and relative height of stenosis on blood velocity and solute dispersion in Jeffrey blood flow within a stenosed artery.
The ratio of relaxation time in a stenosed artery significantly alters blood velocity and solute dispersion, providing a mathematical basis for predicting and optimizing targeted drug delivery to stenosed regions.
Introduction: The research aims to analyst the impact of the ratio of relaxation time, slip velocity and the relative height of stenosis towards the blood velocity and solute dispersion in the Jeffrey blood flow within a stenosed artery. Methods: Generalized Dispersion Model (GDM) is applied into the convective diffusion equation which is then solved to obtain solute concentration and dispersion function. Results and Discussion: When the relative stenosis height increases, there is a slight reduction in blood flow velocity. As time increases, the unsteady dispersion function contracts at the center and expands along the arterial wall. With an increases in the ratio of relaxation time, the dispersion function expands along the arterial wall and contracts at the center. Conclusion: The presence of the ratio of relaxation time in a stenosed artery can disrupt both blood velocity and the dispersion function. This research has the potential to predict drug delivery to specific stenosed regions, thereby enabling more precise and targeted medical treatment.
No takes yet. Share an insight, caveat, or question.
Jaafar et al. (2025) studied Stenosis (mathematical model). Ratio of relaxation time, slip velocity, and relative height of stenosis was evaluated on Blood velocity and unsteady solute dispersion function. In a mathematical model of Jeffrey blood flow, increasing the relative stenosis height reduced blood flow velocity, while an increased ratio of relaxation time expanded the dispersion function along the arterial wall.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: