What question did this study set out to answer?

To determine whether electrocardiographic recordings can remain completely normal in patients with pathologically confirmed acute myocardial infarction.

June 1, 1958A M A Archives of Internal Medicine

The Electrocardiogram in Myocardial Infarction

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Why the study?

Can electrocardiograms be normal in patients with autopsy-proven acute myocardial infarction?

Population

304 cases of myocardial infarction proven at autopsy

Design

Case_series

Authors

MWMorris M. WeissUniversity of Louisville

Discussion

Member takes

Implication

Normal ECG cannot exclude AMI; leaves open its true frequency in larger cohorts.

Key Points

To determine whether electrocardiographic recordings can remain completely normal in patients with pathologically confirmed acute myocardial infarction.
Analyzed clinical electrocardiographic tracings from 304 patients with myocardial infarction confirmed by postmortem pathological examination (N=304).
Correlated electrocardiographic findings with historical clinical observations and experimental animal models evaluating deep myocardial and subendocardial damage.
Literature review demonstrated conflicting evidence, with some clinical series reporting abnormal tracings in nearly all patients while experimental models showed intact tracings during subendocardial infarction.
Postmortem correlation across 304 autopsy cases provides definitive pathological verification to clarify the diagnostic incidence of negative or normal electrocardiograms during active infarction.

Structured PICO

Can electrocardiograms be normal in patients with autopsy-proven acute myocardial infarction?

Population

304 cases of myocardial infarction proven at autopsy

Outcome

Electrocardiogram findings (normal vs abnormal)surrogate

This autopsy-based study investigates whether acute myocardial infarction can occur with a strictly normal electrocardiogram.

Cite This Study

Morris M. Weiss (1958) studied this question.

synapsesocial.com/papers/6a98c301aa63da60ef78bbb2 https://doi.org/10.1001/archinte.1958.00260180116012

View Full Paper

Ask AI

Bookmark

The Electrocardiogram in Myocardial Infarction

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

The Electrocardiogram in Myocardial Infarction

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider