Key result
Indocyanine green near-infrared fluorescence imaging demonstrated a pooled sensitivity of 71% and specificity of 84.6% for detecting sentinel lymph nodes in colorectal cancer.
Why the study?
Does indocyanine green (ICG) near-infrared (NIR) fluorescence accurately detect sentinel lymph nodes in patients with colorectal cancer?
Population
12 studies including 248 patients with Colorectal cancer (CRC)
Design
Meta-analysis
Authors
Loading...
Moderate accuracy limits routine adoption for colorectal sentinel node mapping; leaves open need for prospective validation before practice change.
Meta-Analysis (n=248)
Does indocyanine green (ICG) near-infrared (NIR) fluorescence accurately detect sentinel lymph nodes in patients with colorectal cancer?
Effect estimate: Pooled sensitivity 71%, specificity 84.6%
ICG-NIR fluorescence demonstrates promising sensitivity (71%) and specificity (84.6%) for detecting sentinel lymph nodes in colorectal cancer.
Emile et al. (2017) conducted a meta-analysis in Colorectal cancer (n=248). Indocyanine green (ICG) near-infrared (NIR) fluorescence imaging was evaluated on Sensitivity and specificity in sentinel lymph node detection (Pooled sensitivity 71%, specificity 84.6%). Indocyanine green near-infrared fluorescence imaging demonstrated a pooled sensitivity of 71% and specificity of 84.6% for detecting sentinel lymph nodes in colorectal cancer.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: