Key result
Fetuses with complex congenital heart disease had a significantly higher risk of pregnancy termination compared to those with simple disease (OR 3.485), although multidisciplinary-joint consultation significantly decreased termination rates.
Why the study?
Early diagnosis of congenital heart disease (CHD) can improve the prognosis of neonates with CHD, prompting an evaluation of the value of prenatal diagnosis by comparing pregnancy outcomes.
Does multidisciplinary-joint consultation reduce pregnancy termination rates in fetuses diagnosed with congenital heart disease?
Observational (n=1,492)
No
Does multidisciplinary-joint consultation reduce pregnancy termination rates in fetuses diagnosed with congenital heart disease?
Odds Ratio: 3.485 (95% CI 3.025–4.016)
Absolute Event Rate: 87% vs 35.51%
p-value: p=<0.001
Prenatal diagnosis via ultrasound and multidisciplinary-joint consultation significantly influences pregnancy decisions, reducing termination rates and improving outcomes for fetuses with congenital heart disease.
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May support multidisciplinary consultation in fetal CHD counseling; hypothesis-generating and requires prospective confirmation.
Qiu et al. (2020) conducted an observational in Fetal congenital heart disease (n=1,492). Complex congenital heart disease vs. Simple congenital heart disease was evaluated on Termination of pregnancy (OR 3.485, 95% CI 3.025-4.016, p=<0.001). Fetuses with complex congenital heart disease had a significantly higher risk of pregnancy termination compared to those with simple disease (OR 3.485), although multidisciplinary-joint consultation significantly decreased termination rates.
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