Key result
A rare case of intravascular papillary endothelial hyperplasia on the lower leg presented as a black nodule clinically simulating malignant melanoma, which was differentiated by histopathological examination.
Case Report (n=1)
Intravascular papillary endothelial hyperplasia can present as a black nodule simulating malignant melanoma clinically, but is distinguishable histopathologically.
Black nodules on the leg warrant histopathologic evaluation; this case extends the known presentations of intravascular papillary endothelial hyperplasia.
© 2010 The Authors. doi: 10.2340/00015555-0815 Journal Compilation © 2010 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, Intravascular papillary endothelial hyperplasia (IPEH) was first described by Masson (1) as a neoplastic lesion “vegetant intravascular haemangioendothelioma”. In 1976, Clearkin & Enzinger (2) proposed the term IPEH, which is currently known as a non-neoplastic reactive endothelial proliferation. The lesions are frequently situated in the deep dermis and subcutis of the fingers, head and neck. In subcutaneous localizations the lesion may appear clinically as a small, firm, superficial nodule imparting a red-to-blue discoloration of the overlying skin. We describe here a rare case of IPEH on the lower leg, which resembled malignant melanoma in appearance.
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Kim et al. (2010) conducted a case report in Intravascular Papillary Endothelial Hyperplasia (n=1). Intravascular Papillary Endothelial Hyperplasia was evaluated on Histopathological diagnosis. A rare case of intravascular papillary endothelial hyperplasia on the lower leg presented as a black nodule clinically simulating malignant melanoma, which was differentiated by histopathological examination.
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