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November 13, 2010Critical Care MedicineOpen Access

Decreased mortality resulting from a multicomponent intervention in a tertiary care medical intensive care unit

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Key result

A multicomponent reorganization of a medical intensive care unit was associated with a reduction in ICU mortality from 18.4% to 14.9% (adjusted OR 0.74; 95% CI 0.61-0.91; p=0.003).

Why the study?

Does a multicomponent organizational intervention including increased staffing and 24-hour intensivist coverage reduce mortality in patients admitted to a medical intensive care unit?

Population

3,687 patients admitted to a medical intensive care unit of a tertiary care, academic medical center.

Comparison

Multicomponent organizational intervention… vs Standard care before the organizational change.

Design

Cohort

Follow-up

In-hospital

Authors

GNGiora NetzerUniversity of Maryland, BaltimoreXLXinggang LiuPetroChina Southwest Oil and Gas Field Company (China)CSCarl ShanholtzUniversity of Maryland, Baltimore

Discussion

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Implication

Supports MICU reorganization; leaves open whether benefits are causal or generalizable without randomized confirmation.

Study Design

Type

Observational (n=3,687)

Multicenter

No

Structured PICO

Does a multicomponent organizational intervention including increased staffing and 24-hour intensivist coverage reduce mortality in patients admitted to a medical intensive care unit?

P
Population
3,687 patients admitted to a tertiary care medical intensive care unit before and after a multicomponent organizational intervention.
E
Exposure
Multicomponent organizational intervention including a physical move from a 10-bed to a 29-bed medical intensive care unit with larger patient rooms, initiation of 24-hour critical care specialist coverage, increased respiratory therapist-to-patient ratio, and addition of a clinical pharmacist.
C
Comparator
Standard care before the organizational change (10-bed medical intensive care unit with prior staffing levels).
O
Outcome
Mortality in the medical intensive care unit and in-hospital.hard clinical

Main Result

Odds Ratio: 0.74 (95% CI 0.61–0.91)

Absolute Event Rate: 14.9% vs 18.4%

p-value: p=0.003

A multicomponent reorganization of medical ICU services, including 24-hour intensivist coverage and increased multidisciplinary staffing, significantly reduced ICU and in-hospital mortality.

Cite This Study

Netzer et al. (2010) conducted an observational in Medical intensive care unit patients (n=3,687). Multicomponent organizational intervention vs. Before the organizational change was evaluated on Medical intensive care unit mortality (OR 0.74, 95% CI 0.61-0.91, p=0.003). A multicomponent reorganization of a medical intensive care unit was associated with a reduction in ICU mortality from 18.4% to 14.9% (adjusted OR 0.74; 95% CI 0.61-0.91; p=0.003).

synapsesocial.com/papers/6a98d09a2f1fc3f3d1aef6f4https://doi.org/10.1097/ccm.0b013e3181ffdd2f
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