Larvicidal Efficacy and Characterization of Silver Nanoparticles Derived from Aqueous Leaves Extracts of Trichosanthes tricuspidata against Dengue Vector Ades aegypti

Objectives: The present investigation aims to analyze the larvicidal activity of T. tricuspidata plant extract and silver nanoparticles from aqueous extracts of T. tricuspidata. Methods: silver nanoparticles synthesized from T. tricuspidata leaf extract, were evaluated against larvae of A. aegypti. Synthesis of AgNPs was confirmed using UV–Vis spectroscopy, and characterized using powdered X-ray diffraction, scanning electron microscopy and transmission electron microscopy. Findings: For characterization of green silver nanoparticle UV-visible spectroscopy has been used which yield pointed peak at 454nm. A particle size analyzer was used to characterization of the average size (181nm) distributions in the intensity (57.7%) of silver nanoparticles, and X-ray diffraction (XRD) of planes (111, 200, 220, and 311) intensity (2θ) peaks validated the silver ion\'s cubic structure. The highest mortality was determined from the silver nanoparticles against A. aegypti in the LC50 value of 30.928. Novelty: The nanoparticle synthesized from T. tricuspidata leaf extract was found to excellent toxic effect against the disease transmitting vector mosquitoes. The silver nanoparticles is a rapid, eco-friendly, and a single-step approach and the AgNps formed can be potential mosquito larvicidal agents. Keywords: Larvicidal Activity, Silver Nanoparticles, SEM, T. Tricuspidata, A. Aegypti