Key result
Reintubation (OR 11.155) and prolonged mechanical ventilation were identified as major independent risk factors for the development of sepsis following pediatric congenital heart surgery.
Why the study?
To evaluate the incidence and risk factors associated with sepsis in pediatric patients undergoing congenital heart surgery.
Population
289 pediatric patients who underwent congenital heart surgery
Comparison
28 patients with sepsis vs 261 patients without sepsis
Design
Prospective cohort study
Authors
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Reintubation and prolonged ventilation were associated with sepsis after pediatric congenital heart surgery; hypothesis-generating for extubation optimization trials.
Cohort (n=289)
No
Odds Ratio: 11.155 (95% CI 2.2–56.42)
p-value: p=0.004
Reintubation and prolonged mechanical ventilation are major risk factors for sepsis following pediatric congenital heart surgery, highlighting the importance of optimal extubation strategies to reduce infectious complications.
Yavuz et al. (2019) conducted a cohort in Congenital heart disease requiring surgery (n=289). Reintubation vs. No reintubation was evaluated on Development of sepsis (OR 11.155, 95% CI 2.20-56.42, p=0.004). Reintubation (OR 11.155) and prolonged mechanical ventilation were identified as major independent risk factors for the development of sepsis following pediatric congenital heart surgery.
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