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endocarditis of the native mitral valve. Despite appropriate antibiotic therapy, the clinical course was complicated by acute mitral regurgitation and heart failure requiring valve replacement. This report highlights the diagnostic and therapeutic challenges of pediatric IE in the absence of traditional risk factors and emphasizes the importance of early clinical suspicion, pathogen-directed antimicrobial therapy, and timely surgical intervention.
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Jang et al. (2026) studied this question.
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