Key result
Mortality in neuroleptic malignant syndrome was significantly affected by age (p=0.006), antipsychotic type (p=0.009), therapeutic form (p<0.001), comorbidity (p=0.001), and complications (p=0.001).
Why the study?
Neuroleptic malignant syndrome is a rare life-threatening adverse reaction to antipsychotics with limited literature data, prompting an analysis of risk factors for mortality.
Cohort (n=156)
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Age, antipsychotic type/form, and comorbidities may influence NMS mortality; leaves open causal links and any practice changes.
Balyshev et al. (2023) conducted a cohort in Neuroleptic malignant syndrome (n=156). Risk factors (age, antipsychotic type, therapeutic form, comorbidity, complications) was evaluated on Mortality. Mortality in neuroleptic malignant syndrome was significantly affected by age (p=0.006), antipsychotic type (p=0.009), therapeutic form (p<0.001), comorbidity (p=0.001), and complications (p=0.001).
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