Neuroleptic malignant syndrome, a potentially fatal consequence of neuroleptic use, was characterized through a comprehensive review and analysis of 115 published case reports.
This review analyzes 115 case reports of neuroleptic malignant syndrome across 43 variables to summarize existing literature and guide future research.
Neuroleptic malignant syndrome is a potentially fatal consequence of neuroleptic use that has recently gained wide attention. In this article the authors critically review the previous literature and analyze all case reports in the English-language literature (115 cases) for 43 variables. The results are discussed in light of prior literature, and recommendations are made for future research.
Addonizio et al. (1987) studied this question. Neuroleptic malignant syndrome, a potentially fatal consequence of neuroleptic use, was characterized through a comprehensive review and analysis of 115 published case reports.