Why the study?
What are the clinical features, course, and treatment of neuroleptic malignant syndrome?
What are the clinical features, course, and treatment of neuroleptic malignant syndrome?
This review highlights the clinical features and management of neuroleptic malignant syndrome to improve patient safety when prescribing antipsychotic drugs.
Since the initial description of neuroleptic malignant syndrome (NMS) 40 years ago, a wealth of clinical data has accumulated on the manifestations, course, treatment, and pathogenesis of this uncommon but serious and potentially lethal drug reaction. Nevertheless, vigilance must be maintained, as this disorder remains obscure to many practising physicians. Here, we review the clinical features of NMS to enhance patient safety and reduce physician liability whenever antipsychotic drugs are administered.
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Caroff et al. (2001) studied this question.
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