Key result
Higher red cell distribution width was an independent predictor of impaired coronary collateral circulation in patients with NSTEMI (OR 1.52; 95% CI 1.30-1.78; P<0.001).
Why the study?
Does baseline red cell distribution width (RDW) predict impaired coronary collateral circulation in patients with NSTEMI?
Observational (n=322)
Does baseline red cell distribution width (RDW) predict impaired coronary collateral circulation in patients with NSTEMI?
Odds Ratio: 1.52 (95% CI 1.3–1.78)
p-value: p=<0.001
Higher baseline red cell distribution width is independently associated with impaired coronary collateral circulation in patients presenting with NSTEMI.
RDW was associated with impaired collaterals in NSTEMI; hypothesis-generating and should not yet change practice.
OBJECTIVES: We aimed to investigate the relationship between red cell distribution width (RDW) value and coronary collateral circulation (CCC) in patients with non-ST elevation myocardial infarction (NSTEMI). METHODS: The study population consisted of 322 consecutive patients with NSTEMI. The patients were classified into impaired CCC (group 1, Rentrop grades 0-1) or good CCC (group 2, Rentrop grades 2-3). Baseline RDW was measured as part of the automated complete blood count. RESULTS: The RDW values were significantly higher in patients with impaired CCC than in those with good CCC (17.2 ± 2.3 vs 14.5 ± 2.5, P < .001). In multivariate logistic regression analysis, RDW (odds ratio: 1.52, 95% confidence interval: 1.30-1.78, P < .001), baseline creatine kinase MB (CK-MB), and absence of preinfarction angina were found to be the independent predictors of impaired CCC. In receiver-operating characteristic curve analysis, the RDW value >15.5 yielded an area under curve value of 0.783, with 77% sensitivity and 73% specificity. CONCLUSIONS: Our study results demonstrated that, high RDW, high CK-MB, and absence of preinfarction angina were found to be independent predictors of impaired CCC.
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Tanboğa et al. (2012) conducted an observational in Non-ST Elevation Myocardial Infarction (NSTEMI) (n=322). Red cell distribution width (RDW) was evaluated on Impaired coronary collateral circulation (Rentrop grades 0-1) (OR 1.52, 95% CI 1.30-1.78, p=<0.001). Higher red cell distribution width was an independent predictor of impaired coronary collateral circulation in patients with NSTEMI (OR 1.52; 95% CI 1.30-1.78; P<0.001).
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