Key result
Polycystic ovary syndrome was associated with a higher prevalence of glucose intolerance compared to healthy controls (16.3% vs 8.5%; OR 2.08; P=0.045) during oral glucose tolerance testing.
Why the study?
Does HbA1c accurately detect abnormal glucose metabolism compared to OGTT in women with PCOS?
Observational (n=369)
No
Does HbA1c accurately detect abnormal glucose metabolism compared to OGTT in women with PCOS?
Odds Ratio: 2.08
Absolute Event Rate: 16.3% vs 8.5%
p-value: p=0.045
HbA1c alone is insufficiently sensitive to detect abnormal glucose metabolism in Turkish women with PCOS, indicating that OGTT remains necessary for reliable diagnosis.
HbA1c may underestimate glucose intolerance in PCOS; leaves open whether routine OGTT improves risk stratification.
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Çeli̇k et al. (2013) conducted an observational in Polycystic ovary syndrome (n=369). Polycystic ovary syndrome vs. Women without PCOS was evaluated on Glucose intolerance (impaired glucose tolerance or type 2 diabetes mellitus) during OGTT (OR 2.08, p=0.045). Polycystic ovary syndrome was associated with a higher prevalence of glucose intolerance compared to healthy controls (16.3% vs 8.5%; OR 2.08; P=0.045) during oral glucose tolerance testing.
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