Key result
Esmolol was superior to nitroglycerin in providing surgical dryness, reducing blood loss, and shortening duration during functional endoscopic sinus surgery.
Why the study?
Does esmolol reduce intraoperative bleeding and improve surgical field visibility compared to nitroglycerin in patients undergoing functional endoscopic sinus surgery?
Population
60 patients of American Society of Anesthesiologists I and II undergoing functional endoscopic sinus surgery…
Comparison
Esmolol (ESM) for controlled hypotension vs Nitroglycerin (NTG) for controlled hypotension
Design
Cohort
Follow-up
Intraoperative
Authors
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Esmolol may improve conditions in FESS; hypothesis-generating from cohort data and requires RCT confirmation before practice change.
RCT (n=60)
Does esmolol reduce intraoperative bleeding and improve surgical field visibility compared to nitroglycerin in patients undergoing functional endoscopic sinus surgery?
Esmolol is superior to nitroglycerin for controlled hypotension during functional endoscopic sinus surgery, providing better surgical visibility and less bleeding without reflex tachycardia.
Yoganarasimha et al. (2016) conducted an RCT in Nasal disorders requiring functional endoscopic sinus surgery (n=60). Esmolol vs. Nitroglycerin was evaluated on Mean change in heart rate, blood pressure, surgical bleeding, and duration of hypotensive anesthesia. Esmolol was superior to nitroglycerin in providing surgical dryness, reducing blood loss, and shortening duration during functional endoscopic sinus surgery.
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