What question did this study set out to answer?

To evaluate the distribution of blood lipid levels and identify demographic and metabolic factors that influence lipid alterations across a large population.

November 8, 2022Frontiers in Cardiovascular MedicineOpen Access

Analysis of blood lipid changes and influencing factors in physical examination population of a city in central China

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Authors

BZBoya Zhu WWWenjing Wang MLMengying Li

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Overview

Cross-sectional study reveals age, fasting glucose, and BMI differentially alter blood lipid profiles in Chinese adults, suggesting sex-specific approaches for managing dyslipidemia risk.

Key Points

To evaluate the distribution of blood lipid levels and identify demographic and metabolic factors that influence lipid alterations across a large population.
Analyzed cross-sectional physical examination data from N=91,480 participants (59,165 females, mean age 51.71 ± 10.82 years) in Wuhan, China in 2018.
Employed population averages to evaluate lipid distributions and applied quantile regression to assess relationships between physiological indexes and lipid metrics.
Fasting plasma glucose showed the largest quantile regression coefficient, and body mass index showed positive effects on total cholesterol, triglycerides, and low-density lipoprotein cholesterol.
Age positively influenced total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol in males, while positively influencing all four lipid indexes in females.
Body mass index exerted a greater influence on lipid levels in males than females, whereas total cholesterol and low-density lipoprotein cholesterol in females were more sensitive to age, yielding higher lipid levels in older females than in older males.

Cite This Study

Zhu et al. (2022) studied this question.

synapsesocial.com/papers/6a98efd9dea2d226f518eb56 https://doi.org/10.3389/fcvm.2022.996148

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November 8, 2022Frontiers in Cardiovascular MedicineOpen Access

Analysis of blood lipid changes and influencing factors in physical examination population of a city in central China

View Full Paper

Ask AI

Bookmark

Authors

BZBoya Zhu WWWenjing Wang MLMengying Li

Discussion

Member takes

Overview

Cross-sectional study reveals age, fasting glucose, and BMI differentially alter blood lipid profiles in Chinese adults, suggesting sex-specific approaches for managing dyslipidemia risk.

Key Points

To evaluate the distribution of blood lipid levels and identify demographic and metabolic factors that influence lipid alterations across a large population.
Analyzed cross-sectional physical examination data from N=91,480 participants (59,165 females, mean age 51.71 ± 10.82 years) in Wuhan, China in 2018.
Employed population averages to evaluate lipid distributions and applied quantile regression to assess relationships between physiological indexes and lipid metrics.
Fasting plasma glucose showed the largest quantile regression coefficient, and body mass index showed positive effects on total cholesterol, triglycerides, and low-density lipoprotein cholesterol.
Age positively influenced total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol in males, while positively influencing all four lipid indexes in females.
Body mass index exerted a greater influence on lipid levels in males than females, whereas total cholesterol and low-density lipoprotein cholesterol in females were more sensitive to age, yielding higher lipid levels in older females than in older males.

Cite This Study

Zhu et al. (2022) studied this question.

synapsesocial.com/papers/6a98efd9dea2d226f518eb56 https://doi.org/10.3389/fcvm.2022.996148

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