Key result
Low ankle-brachial index (<0.90) was significantly associated with more severe coronary artery disease, including a higher prevalence of triple vessel disease and severe stenosis.
Why the study?
In patients clinically suspected of having CAD, the relationship and interaction between DM and PAD remain unknown.
Does a low ankle-brachial index (<0.90) predict increased angiographic severity of coronary artery disease in adult patients with diabetes mellitus?
Observational (n=50)
No
Does a low ankle-brachial index (<0.90) predict increased angiographic severity of coronary artery disease in adult patients with diabetes mellitus?
Answers are grounded in this paper and cite their sources.
A low ankle-brachial index (<0.90) serves as a simple, noninvasive bedside predictor of severe angiographic coronary artery disease in patients with diabetes mellitus.
Background Coronary artery disease (CAD) due to atherosclerosis is like an epidemic in India. The role of diabetes mellitus (DM) with CAD is believed to be as important as CAD itself. Owing to the similar vascular involvement, patients with DM were frequently combined with peripheral artery disease (PAD). Although in outpatients, clinically suspected of having CAD, the relationship and interaction between DM and PAD remain unknown. Aim and objective The aim and objective of this study is to evaluate the relation of the ankle-brachial index (ABI) with the angiographic characteristics of CAD in patients with DM. Materials and methods This is a tertiary hospital study in which 50 adult patients were admitted and taken according to inclusion and exclusion criteria for the study. All patients in this study population underwent ABI measurement and coronary angiography was done. Patients were subdivided into two groups according to ABI, that is, patients with ABI >0.90 and ABI <0.90. Results There was a significant relationship between low ABI and severity of CAD. Low ABI group patients had a more severe form of CAD with a higher prevalence of triple vessel diseases, severe stenosis, and more involvement of the left anterior descending (LAD)artery. Risk factors like hypertension, diabetes mellitus, and low ABI were predictors of significant severe stenosis of coronary arteries. Conclusion Low ABI is a surrogate index of the severity of CAD. So it could be used in our everyday clinical cardiology practice as a noninvasive, easy, and cheap bedside test to assess and predict the severity of CAD. How to cite this article Mohan G, Mohan G, Singh B, et al. Angiographic Assessment of Coronary Artery Disease and Its Correlation with Ankle-brachial Index in Patients with Diabetes Mellitus. AMEI's Curr Trends Diagn Treat 2020;4(2):69–73.
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Mohan et al. (2021) conducted an observational in Coronary artery disease and Diabetes Mellitus (n=50). Low ankle-brachial index (<0.90) vs. Ankle-brachial index >0.90 was evaluated on Severity of coronary artery disease (angiographic characteristics). Low ankle-brachial index (<0.90) was significantly associated with more severe coronary artery disease, including a higher prevalence of triple vessel disease and severe stenosis.
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