Key result
Ankle-brachial index was significantly lower in peripheral arterial disease patients with significant coronary artery disease compared to those without coronary artery disease (0.37 vs 0.75, p<0.001).
Why the study?
Atherosclerosis is a generalized disease involving coronary and peripheral arteries, and the relationship between ankle-brachial index and coronary artery disease in patients with peripheral arterial disease was unclear.
Does the ankle-brachial index predict the presence of coronary artery disease in patients with peripheral arterial disease?
Observational (n=58)
Single-blind
No
Does the ankle-brachial index predict the presence of coronary artery disease in patients with peripheral arterial disease?
Answers are grounded in this paper and cite their sources.
A lower ankle-brachial index is significantly associated with the presence of coronary artery disease in patients with peripheral arterial disease.
Most common cause of Peripheral Arterial Disease (PAD) is atherosclerosis. Atherosclerosis is a generalized disease, also involving coronary and carotid arteries. Often atherosclerotic coronary artery disease (CAD) is associated with PAD. This prospective observational study was conducted in the National Institute of Cardiovascular Diseases, Dhaka, Bangladesh, during July 2004 to June 2005. Total 58 patients with PAD were included in the study. Patients were classified as group I having normal coronary artery, group II insignificant CAD (Left main <50% stenosis, others <70% stenosis) and group III, significant CAD (Left main ≥50% stenosis, others ≥70% stenosis). Ankle-brachial index was significantly low (0.75±0.25 Vs 0.37±0.40) in the patients with coronary artery disease (Group II and III) compare to non-CAD (P =0.001).This study suggests that ankle-brachial index (ABI) have significant relation with the presence of CAD. Key words: Ankle-Brachial Index; peripheral arterial disease DOI: 10.3329/uhj.v6i1.7186University Heart Journal Vol.6(1) 2010 pp.23-25
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Habib et al. (1970) conducted an observational in Peripheral Arterial Disease (n=58). Coronary Artery Disease vs. No Coronary Artery Disease was evaluated on Mean Ankle-Brachial Index (p=<0.001). Ankle-brachial index was significantly lower in peripheral arterial disease patients with significant coronary artery disease compared to those without coronary artery disease (0.37 vs 0.75, p<0.001).
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