Key result
Diabetes was associated with a stronger correlation between epicardial fat thickness and GENSINI score in NSTEMI patients compared with non-diabetics.
Why the study?
Although epicardial fat thickness correlates with coronary artery disease severity, the potential impact of diabetes on this relationship was not fully investigated.
Observational (n=52)
In patients with NSTEMI, the correlation between epicardial fat thickness and coronary artery disease severity is significantly stronger in those with diabetes.
Answers are grounded in this paper and cite their sources.
Suggests epicardial fat merits study as CAD severity marker in diabetic NSTEMI; hypothesis-generating and should not change practice.
Background: there is a strong relationship between epicardial fat thickness and severity of coronary artery disease. The impact of diabetes on severity of coronary artery disease (CAD) is well known. The possible impact of diabetes on the relationship between EFT and severity of CAD was not fully investigated. Patients and Methods: The study included 52 patients with NSTEMI (mean age: 54.3±6.7years). Patients were classified into two groups according to presence of diabetes (diabetic group (24 patients) and non-diabetic group (28 patients)). EFT was measured by transthoracic echocardiography on the right ventricle in individuals having the left lateral decubitus position GENSINI score was used to define the severity of CAD. Results: Diabetic patients had higher EFT values compared with non-diabetics (p < 0.05). EFT is independently associated with diabetes and GENSINI score in all patients (p < 0.05, for all). When patients were divided into two groups, as diabetic and non-diabetic, the association between EFT and GENSINI score was stronger in diabetic patients compared with non-diabetics (r = 0.6618; p< 0.001vs. r = 0.330; p = 0.04). Conclusion: Epicardial fat thickness is associated with GENSINI score in both diabetic and non-diabetic patients suffering from NSTEMI. Furthermore, there is a stricter relationship between EFT and GENSINI score in diabetic patients
No takes yet. Share an insight, caveat, or question.
Aboleineen et al. (2019) conducted an observational in NSTEMI (n=52). Diabetes vs. Non-diabetic was evaluated on Correlation between epicardial fat thickness and GENSINI score (r = 0.6618 (diabetic) vs r = 0.330 (non-diabetic), p=<0.001 vs 0.04). Diabetes was associated with a stronger correlation between epicardial fat thickness and GENSINI score in NSTEMI patients compared with non-diabetics.
Synapse has enriched 10 related papers. Consider them for comparative context: