C-Reactive Protein and Coronary Artery Calcification
Why the study?
Is plasma C-reactive protein associated with coronary artery calcification in asymptomatic subjects?
Population
914 asymptomatic subjects in the Study of Inherited Risk of Coronary Atherosclerosis (SIRCA)
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
No independent CRP-CAC link after BMI adjustment; leaves open whether they capture complementary CV risk aspects in asymptomatic adults.
Structured PICO
Is plasma C-reactive protein associated with coronary artery calcification in asymptomatic subjects?
P
Population
914 asymptomatic subjects in the Study of Inherited Risk of Coronary Atherosclerosis (SIRCA)
I
Intervention
Plasma C-reactive protein (CRP) levels
O
Outcome
Coronary artery calcification (CAC)surrogate
Plasma CRP levels are not independently associated with coronary artery calcification burden after adjusting for BMI, suggesting CRP and CAC provide distinct information regarding cardiovascular risk.
Cite This Study
Reilly et al. (2003) studied this question.