Key result
The provided abstract is truncated and does not report quantitative results comparing serum cystatin-C to serum creatinine in subjects with type 1 diabetes.
Observational
Incomplete data preclude cystatin-C adoption over creatinine for T1D renal assessment; leaves open need for complete comparative analyses.
Glomerular filtration rate (GFR) is considered the best marker of renal function, and its estimation using inulin or 51Cr-EDTA is considered the “gold standard.” Such determination is inconvenient and often replaced by an estimate of creatinine clearance (CrCl) derived from the formula of Cockroft and Gault (CG). Serum cystatin-C was recently proposed as a reliable alternative routine marker of GFR in pediatric, adult, and elderly subjects (1–4). Although Dharnidharka et al. (5) thouroughly review the issue of comparing cystatin-C and creatinine in relation to reference GFR measurements, few reports deal with the comparison of serum creatinine and cystatin-C in diabetic patients …
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Buysschaert et al. (2003) conducted an observational in Type 1 Diabetes. Serum Cystatin-C vs. Serum Creatinine was evaluated. The provided abstract is truncated and does not report quantitative results comparing serum cystatin-C to serum creatinine in subjects with type 1 diabetes.
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