Key result
The index of cardioelectrophysiological balance was significantly higher in patients with severe acute ischemic stroke (NIHSS ≥16) compared to those with less severe stroke (3.97 vs 3.43, P=0.0024).
Why the study?
The index of cardioelectrophysiological balance (iCEB) is a newly defined risk marker for arrhythmias, but its relationship with stroke severity in acute ischemic stroke patients had not been evaluated.
Is the index of cardioelectrophysiological balance (iCEB) associated with stroke severity in patients with acute ischemic stroke?
Observational (n=105)
Is the index of cardioelectrophysiological balance (iCEB) associated with stroke severity in patients with acute ischemic stroke?
Absolute Event Rate: 3.97% vs 3.43%
p-value: p=0.0024
A higher index of cardioelectrophysiological balance (iCEB) on admission is associated with greater stroke severity in patients with acute ischemic stroke.
iCEB may help stratify acute ischemic stroke severity; leaves open its prognostic or therapeutic role pending prospective validation.
BACKGROUND: The index of cardioelectrophysiological balance (iCEB), measured as QT interval divided by QRS duration, has recently been defined as a new risk marker for arrhythmias. Increased or decreased iCEB is associated with malignant ventricular arrhythmias. AIM: In this study, we aimed to investigate the relationship between iCEB and stroke severity in patients with acute ischemic stroke. METHODS: The study comprised 105 adult patients (males, 58; females, 47; 69 ± 15 years) with acute ischemic stroke. Nine patients were excluded. Patients were divided into two groups based on the calculated National Institutes of Health Stroke Scale (NIHSS) score (Group 1, NIHSS score <16; Group 2, NIHSS score ≥16). Demographic, clinical, and laboratory data for all patients were collected. Electrocardiography (ECG) was recorded from all patients on admission to the neurology care unit. iCEB (QT/QRS) was calculated from the 12-lead electrocardiogram. RESULTS: There were no significant differences among the demographic parameters of patients. iCEB score was significantly higher in Group 2 patients than Group 1 patients (3.97 ± 0.61 vs 3.43 ± 0.57, P = 0.0024). CONCLUSION: Our results suggested that iCEB is associated with stroke severity on admission in patients with acute ischemic stroke. It is known that high iCEB is associated with torsade de pointes (TdP), ventricular tachycardia.
No takes yet. Share an insight, caveat, or question.
Öztürk et al. (2020) conducted an observational in Acute ischemic stroke (n=105). Severe acute ischemic stroke (NIHSS ≥16) vs. Mild/moderate acute ischemic stroke (NIHSS <16) was evaluated on Index of cardioelectrophysiological balance (iCEB) score (p=0.0024). The index of cardioelectrophysiological balance was significantly higher in patients with severe acute ischemic stroke (NIHSS ≥16) compared to those with less severe stroke (3.97 vs 3.43, P=0.0024).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: