Key result
The modified frailty index-5 (mFI-5) was independently associated with an increased risk of 30-day post-operative infectious complications (OR 2.00) after intestinal-cutaneous fistula repair.
Why the study?
Post-operative infectious complications after intestinal-cutaneous fistula repair represent a substantial burden with widely varying outcomes in the literature.
Does the modified frailty index-5 (mFI-5) score predict 30-day post-operative infectious complications in patients undergoing surgery for intestinal-cutaneous fistula?
Population
4,197 patients who underwent intestinal-cutaneous fistula repair
Comparison
Risk assessed across modified frailty index-5 (mFI-5) scores
Design
Nationwide retrospective cohort study
Follow-up
30 days
Authors
Loading...
mFI-5 identifies higher infection risk after ICF repair; leaves open whether frailty optimization reduces complications.
Cohort (n=4,197)
Yes
Does the modified frailty index-5 (mFI-5) score predict 30-day post-operative infectious complications in patients undergoing surgery for intestinal-cutaneous fistula?
Odds Ratio: 2 (95% CI 1.25–3.21)
p-value: p=0.004
The modified frailty index-5 (mFI-5) is a strong independent predictor of 30-day infectious complications, particularly surgical site infections and pneumonia, after intestinal-cutaneous fistula repair.
Alser et al. (2021) conducted a cohort in Intestinal-cutaneous fistula (ICF) (n=4,197). Modified Frailty Index-5 (mFI-5) vs. Lower mFI-5 score was evaluated on 30-day infectious complications (surgical site infection, sepsis, pneumonia, and urinary tract infection) (OR 2.00, 95% CI 1.25-3.21, p=0.004). The modified frailty index-5 (mFI-5) was independently associated with an increased risk of 30-day post-operative infectious complications (OR 2.00) after intestinal-cutaneous fistula repair.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: