Key result
Ischemic heart disease was associated with significantly reduced left ventricular ejection fraction and increased end-systolic and end-diastolic volumes compared to healthy controls across all degrees of ischemia (p < 0.05).
Why the study?
Left ventricular function and volumes carry major diagnostic and prognostic importance in ischemic heart disease, which is characterized by systolic dysfunction and reduced cardiac output.
Do echocardiographic parameters of left ventricular function differ between patients with ischemic heart disease and healthy individuals?
Observational (n=481)
No
Do echocardiographic parameters of left ventricular function differ between patients with ischemic heart disease and healthy individuals?
Absolute Event Rate: 41.89% vs 67.69%
p-value: p=<0.05
Ischemic heart disease is associated with significant alterations in left ventricular volumes and ejection fraction compared to healthy individuals, reflecting underlying systolic and diastolic dysfunction.
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Echocardiographic LV changes may aid severity assessment in IHD; leaves open whether diastolic dysfunction prevalence refines risk stratification.
Mohammed et al. (2022) conducted an observational in Ischemic heart disease (n=481). Ischemic heart disease vs. Healthy individuals was evaluated on Left ventricular ejection fraction (LVEF) in ischemia degrees 1 and 2 (p=<0.05). Ischemic heart disease was associated with significantly reduced left ventricular ejection fraction and increased end-systolic and end-diastolic volumes compared to healthy controls across all degrees of ischemia (p < 0.05).
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