Key result
Among 157 rotavirus-positive samples from Brazilian children, 73.3% of typeable strains were common genotypes (G1P[8], G2P[4], G3P[8], G4P[8]), while 15.9% involved the emerging G9 genotype.
Observational (n=157)
Yes
The study identifies the prevalence of common and unusual rotavirus genotypes, including G9 strains, in Rio de Janeiro between 1997 and 1999.
Offers pre-vaccine baseline for Brazilian rotavirus genotypes; leaves open current G9 prevalence and vaccine impact.
One hundred fifty-seven (23%; n = 678) rotavirus-positive stool samples were collected between March 1997 and December 1999 in the cites of Rio de Janeiro and Niterói. Rotaviruses in 143 (91%) samples were genotyped by reverse transcription-PCR for G and/or P specificity. Rotaviruses in the majority of G-P-typeable samples (73.3%; 74 of 101) were identified as having globally common genotypes G1P[8], G2P[4], G3P[8], and G4P[8]. Unusual strains such as G1P[9], G2[P8], G3P[9], and G9P[4] strains were detected in 8.9% (9 of 101) of the samples. Genotypes G9P[8], G9P[6], and a mixture of G9 and other G or P types represented 15.9% (25 of 157) of the isolates. Mixed infections were detected in 25 (15.9%) samples, and rotaviruses in 15 samples (9.6%) were not typed.
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Santos et al. (2003) conducted an observational in Acute diarrhea (rotavirus infection) (n=157). Rotavirus strain surveillance was evaluated on Rotavirus G and P genotype distribution. Among 157 rotavirus-positive samples from Brazilian children, 73.3% of typeable strains were common genotypes (G1P[8], G2P[4], G3P[8], G4P[8]), while 15.9% involved the emerging G9 genotype.
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