This is the authors' abstract. We don't add key points for this paper.
Recognition with a twist: The acid-initiated polymerization of dipeptide-derived isocyanides (see scheme) is found to be an exceptionally stereospecific process that requires a helical template. The reaction is very sensitive to the acid concentration. At high acid concentrations, the template is destroyed and a competing cyclization reaction becomes predominant.
No takes yet. Share an insight, caveat, or question.
Metselaar et al. (2005) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: