Enantioselective Synthesis of the Spirotetracyclic Carbon Core of Mangicols by Using a Stereoselective Transannular Diels–Alder Strategy

“TADA!” is not the trumpet fanfare but the transannular Diels–Alder reaction concluding the synthesis of the tetracyclic core of the mangicols, a family of marine sesterterpenes. Further highlights in the synthesis include a novel chlorination and an intramolecular Nozaki–Hiyama–Kishi coupling reaction. Bn=benzyl.