Key result
Phylogenetic analysis of HCV strains from Peruvian patients revealed a crossover event in the NS5B protein, indicating intratypic genetic recombination.
Population
Four Hepatitis C virus (HCV) strains isolated from Peruvian patients
Design
Other
Authors
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May complicate HCV genotyping and therapy; leaves open recombination prevalence and impact in diverse populations.
Observational (n=4)
Evidence of intratypic recombination in natural HCV populations may impact genotype classification, laboratory diagnosis, and treatment strategies.
Colina et al. (2004) conducted an observational in Hepatitis C virus (HCV) infection (n=4). HCV strains was evaluated on Congruence of HCV genotyping and evidence of genetic recombination. Phylogenetic analysis of HCV strains from Peruvian patients revealed a crossover event in the NS5B protein, indicating intratypic genetic recombination.
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