Key result
Classic risk factors including older age, urban residence, female sex, hypertension, diabetes, and HIV infection were independently associated with a 12.2% (95% CI 10.2-14.2) overall prevalence of CKD.
Why the study?
The prevalence of CKD in African American individuals is high, but whether this applies to native populations in sub-Saharan Africa remains unclear.
Cross-Sectional
The burden of CKD is substantial (>11%) in South Kivu, DRC, predominantly in urban areas and driven by classic risk factors including hypertension and diabetes.
Supports targeted CKD surveillance in sub-Saharan Africa; leaves open generalizability and causal factors pending prospective data.
BACKGROUND: The prevalence of chronic kidney disease (CKD) in African American individuals is high but whether this applies to native populations in sub-Saharan Africa is unclear. METHODS: and/or albuminuria (albumin-to-creatinine ratio ≥30 mg/g). RESULTS: was 5.4% (95% CI, 4.2-6.7). The prevalence of albuminuria was 6.6% (95 % CI, 5.1-8.1). The overall prevalence of CKD was 12.2% (95% CI, 10.2-14.2) according to CKD-EPIcr. Factors independently associated with CKD-EPIcr were older age (adjusted odds ratio [aOR], 1.05 [1.04-1.07]), urban residence (aOR 1.86 [1.18-2.95]), female sex (aOR 1.66 [1.04-2.66]), hypertension (aOR 1.90 [1.15-3.12]), diabetes (aOR 2.03 [1.02-4.06]), and HIV infection (10.21 [2.75-37.85]). The results based on eGFRcys or eGFRcr-cys were largely consistent with the preceding. CONCLUSION: Overall, the burden of CKD is substantial (>11%), predominantly in the urban area, and largely driven by classic risk factors (gender, aging, HIV, hypertension, and diabetes).
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Masimango et al. (2020) conducted a cross-sectional in Chronic kidney disease (CKD). Classic risk factors (older age, urban residence, female sex, hypertension, diabetes, HIV infection) was evaluated on Overall prevalence of CKD according to CKD-EPIcr (95% CI 10.2-14.2). Classic risk factors including older age, urban residence, female sex, hypertension, diabetes, and HIV infection were independently associated with a 12.2% (95% CI 10.2-14.2) overall prevalence of CKD.
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