What question did this study set out to answer?

To develop and evaluate bioactive, amorphous calcium phosphate-based polymeric composites designed to promote tooth mineral regeneration through ion release and biocompatible interfacial behavior.

September 14, 2011Journal of Functional BiomaterialsOpen Access

Bioactive Polymeric Composites for Tooth Mineral Regeneration: Physicochemical and Cellular Aspects

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Authors

DŠDrago Škrtić JAJoseph M. Antonucci

Discussion

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Overview

In vitro evaluation reveals sustained ion release and favorable biocompatibility of amorphous calcium phosphate composites, highlighting potential for tooth and bone mineral regeneration.

Key Points

To develop and evaluate bioactive, amorphous calcium phosphate-based polymeric composites designed to promote tooth mineral regeneration through ion release and biocompatible interfacial behavior.
Formulated non-degradable polymeric composites combining acrylic monomer systems and amorphous calcium phosphate (ACP) through photochemical or chemically activated polymerization.
Evaluated material physicochemical properties, interfacial filler-polymer interactions, unreacted monomer leachability, and in vitro cellular responses.
Exposure of ACP-containing composites to aqueous environments induced sustained calcium and phosphate ion release, generating local supersaturation conditions that promoted spontaneous conversion to thermodynamically stable apatite.
Physicochemical profiling and cellular evaluations confirmed favorable biocompatibility and structural integrity suitable for bases, liners, orthodontic adhesives, and endodontic sealers.

Cite This Study

Škrtić et al. (2011) studied this question.

synapsesocial.com/papers/6a992a321c4dac29babd57f8 https://doi.org/10.3390/jfb2030271

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September 14, 2011Journal of Functional BiomaterialsOpen Access

Bioactive Polymeric Composites for Tooth Mineral Regeneration: Physicochemical and Cellular Aspects

View Full Paper

Ask AI

Bookmark

Authors

DŠDrago Škrtić JAJoseph M. Antonucci

Discussion

Member takes

Overview

In vitro evaluation reveals sustained ion release and favorable biocompatibility of amorphous calcium phosphate composites, highlighting potential for tooth and bone mineral regeneration.

Key Points

To develop and evaluate bioactive, amorphous calcium phosphate-based polymeric composites designed to promote tooth mineral regeneration through ion release and biocompatible interfacial behavior.
Formulated non-degradable polymeric composites combining acrylic monomer systems and amorphous calcium phosphate (ACP) through photochemical or chemically activated polymerization.
Evaluated material physicochemical properties, interfacial filler-polymer interactions, unreacted monomer leachability, and in vitro cellular responses.
Exposure of ACP-containing composites to aqueous environments induced sustained calcium and phosphate ion release, generating local supersaturation conditions that promoted spontaneous conversion to thermodynamically stable apatite.
Physicochemical profiling and cellular evaluations confirmed favorable biocompatibility and structural integrity suitable for bases, liners, orthodontic adhesives, and endodontic sealers.

Cite This Study

Škrtić et al. (2011) studied this question.

synapsesocial.com/papers/6a992a321c4dac29babd57f8 https://doi.org/10.3390/jfb2030271

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