What question did this study set out to answer?

To evaluate the diagnostic accuracy of the BiliChek transcutaneous bilirubin device against laboratory total serum bilirubin measurements in a predominantly Hispanic neonatal cohort.

July 1, 2002PEDIATRICS

Assessment of a Transcutaneous Device in the Evaluation of Neonatal Hyperbilirubinemia in a Primarily Hispanic Population

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Authors

WEWilliam D. EngleSeattle Children's Hospital GJGregory L. JacksonMarche Polytechnic University DSDorothy SendelbachSouthwestern Medical Center

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Implication

Comparative study reveals transcutaneous bilirubin monitors systematically underestimate serum bilirubin in Hispanic neonates, suggesting limited utility at higher clinical thresholds.

Key Points

To evaluate the diagnostic accuracy of the BiliChek transcutaneous bilirubin device against laboratory total serum bilirubin measurements in a predominantly Hispanic neonatal cohort.
Assessed 248 Hispanic and 56 non-Hispanic neonates using transcutaneous BiliChek determinations within 30 minutes of blood sampling for total serum bilirubin (TSB).
Measured TSB via the diazo Jendrassik-Grof with blank method in a central laboratory and analyzed device agreement using Bland-Altman plots and the Bradley-Blackwood test.
TSB concentrations reached or exceeded 15 mg/dL in 31% of the Hispanic neonates evaluated.
The BiliChek device systematically underestimated TSB levels, with bias becoming markedly more pronounced when serum concentrations exceeded 10 mg/dL.
High sensitivity for detecting TSB >10 mg/dL or >15 mg/dL occurred only at low transcutaneous cutoff thresholds that classified very few infants.

Cite This Study

Engle et al. (2002) studied this question.

synapsesocial.com/papers/6a992caa24d3faa49b74a135 https://doi.org/10.1542/peds.110.1.61

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Implication

Comparative study reveals transcutaneous bilirubin monitors systematically underestimate serum bilirubin in Hispanic neonates, suggesting limited utility at higher clinical thresholds.

Assessment of a Transcutaneous Device in the Evaluation of Neonatal Hyperbilirubinemia in a Primarily Hispanic Population

Discussion

Member takes

Implication

Key Points

Cite This Study

Assessment of a Transcutaneous Device in the Evaluation of Neonatal Hyperbilirubinemia in a Primarily Hispanic Population

Discussion

Member takes

Implication

Key Points

Cite This Study

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