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Chiral induced spin selectivity (CISS) is a phenomenon wherein chiral materials preferentially transmit electrons of one spin over the other. Although interest in CISS is high and growing, its implementation in reticular frameworks, such as metal–organic frameworks (MOFs) and covalent organic frameworks (COFs), remains nascent. This review highlights advances in chiral reticular frameworks exhibiting CISS, emphasizing their intrinsic advantages rooted in modularity, tunability, and crystallinity. We examine reported examples across MOFs, COFs, and related crystalline systems, identify features correlated with high spin selectivity, and propose tentative design principles. By surveying this emerging intersection of reticular chemistry and chirality-induced spin selectivity, we aim to stimulate further exploration of chiral frameworks as next-generation spin filters.
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