A liquid crystal-based photochromic coating was formulated to enable direct visualization of shear stress in flowing blood. The coating was comprised of a low durometer silicone rubber elastomer combined with a cholesteric liquid crystal to expand the functional shearsensing range and improve its durability when exposed to viscous flow. The coating was evaluated with black and red opaque viscous fluids as well as blood for spatial resolution and sensitivity. Experiments were conducted in rectangular channels and a cylindrical Taylor-Couette device with shear stress up to 300 dyne/cm2 in blood, and 3000 dyne/cm2 in glycerol. The results illustrated the feasibility of a liquid crystal based shear stress sensor for visualizing the spatial distribution of biologically relevant shear stress.
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Gottlieb et al. (2009) studied this question.
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