Why the study?
Does amiodarone use during pregnancy and breastfeeding cause adverse effects in neonates?
Population
5 pregnant women receiving amiodarone (2 also during breastfeeding) and their neonates
Design
Case_series
Follow-up
8 months up to 5 years
Authors
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May support neonatal thyroid monitoring with amiodarone lactation; leaves open risk magnitude from case-level data.
Does amiodarone use during pregnancy and breastfeeding cause adverse effects in neonates?
Amiodarone use during pregnancy and lactation carries a risk of neonatal hypothyroidism, necessitating administration at the lowest possible dose and close thyroid function monitoring.
Plomp et al. (1992) studied this question.
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