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September 3, 2026The Journal of Maternal-Fetal & Neonatal MedicineOpen Access

Comparative outcomes and predictive factors in vacuum, forceps, and sequential vacuum-forceps operative vaginal deliveries

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Authors

XCXinjuan ChenJCJinhui CuiLLLing Li

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Overview

Retrospective study reveals increased maternal and neonatal complications with sequential vacuum-forceps delivery, suggesting critical risks associated with combined instruments.

Key Points

  • To evaluate maternal, intrapartum, and neonatal outcomes across different operative vaginal delivery modalities and identify predictive factors using machine learning alongside traditional statistics.
  • Retrospectively analyzed 967 singleton deliveries at a single tertiary center across three modalities: vacuum (n = 208), forceps (n = 706), and sequential vacuum + forceps (n = 53).
  • Compared outcomes using ANOVA and chi-square tests, and trained a Random Forest classifier evaluated by accuracy, AUC, and Cohen’s κ to rank predictors of delivery modality.
  • Sequential vacuum + forceps delivery was associated with significantly longer decision-to-delivery intervals (26.9 min vs. 17.7 min for vacuum and 16.8 min for forceps, p < 0.001) and higher rates of severe perineal laceration (73.6% vs. 34.1% and 47.5%, p < 0.001).
  • Neonates delivered via sequential vacuum + forceps experienced worse outcomes, including lower Apgar scores, higher rates of cephalohematoma, hyperbilirubinemia, and increased neonatal transfer rates.
  • The Random Forest model achieved 73.7% accuracy (AUC 0.758), identifying second-stage duration, decision-to-delivery time, lactate, and base excess as the top predictors of delivery mode.

Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6a9934ea636c6408cfa7ca42https://doi.org/10.1080/14767058.2026.2724778
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Severe Neonatal Morbidity in Forceps versus Vacuum Birth among Individuals with Previous Cesarean Birth: A Population-Based Retrospective Cohort Study2025
  2. 2Operative vaginal deliveries – a relic of the past or a promising prospect?2023 · 1 citations
  3. 3Operative Vaginal Delivery Compared to Cesarean After Failed Labor: A Population-Based Analysis of Neonatal and Maternal Outcomes2026
  4. 4Maternal and Neonatal Morbidity with Sequential Instrumental Delivery as Compared to the Single-use at Operative Vaginal Delivery: A Retrospective Study2026
  5. 5Preterm assisted vaginal births and associated maternal and neonatal outcomes: A retrospective study in a tertiary hospital2026