Design and Characterization of an Active-Matrix Kirigami Bioprobe

The Kirigami approach enables superior stretchability in flexible films despite the use of inelastic materials. Kirigami-based bioprobe devices have demonstrated stable biosignal recordings from tissues such as the heart and brain; however, scaling to high-density multichannel systems remains limited by passive interconnection architectures. Here, we propose an active-matrix Kirigami bioprobe device employing a biocompatible polyimide substrate and amorphous indium-gallium-zinc oxide (IGZO) thin-film transistors (TFTs) while maintaining mechanical flexibility. Finite element simulations confirmed stress distributions in the Kirigami structure, optimizing TFT placement. The device fabrication was carried out using thin-film processes for polyimide and IGZO, independently developed and evaluated. The results demonstrate the feasibility of integrating active-matrix circuitry into a stretchable Kirigami film platform, enabling reduced interconnections and improved scalability for future high-density Kirigami-based bioelectronic interfaces.