Full-mouth rehabilitation with orthodontic treatment for Down syndrome patient with severe malocclusion: a case report

Down syndrome is a representative developmental disorder associated with craniofacial growth deficiency, increased periodontal risk, and low bone density, all of which complicate prosthodontic and implant treatment.This case report describes a fixed prosthetic rehabilitation in a patient with Down syndrome, severe malocclusion, and a history of cleft palate surgery.Orthodontic treatment using implants as absolute anchorage was performed for 2 years and 6 months.However, due to multiple limitations, posterior crossbite could not be completely corrected.Nevertheless, functional harmony was achieved by establishing a normal anterior occlusal relationship.Based on Dawson's occlusal concept, this case suggests that even with residual posterior crossbite, functionally stable outcomes may be obtained through appropriate prosthetic design and anterior occlusal stability.This case highlights the importance of balancing therapeutic compromise and functional stability in full-mouth rehabilitation of patients with developmental disabilities.(