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September 3, 2026International Journal of Transgender Health

Comparative evaluation of indigenous aromatherapy and nicotine replacement therapy for nicotine dependence among transgender women in Puducherry: a randomized controlled trial

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Authors

LSL. S. SidhuSMSenthil M.SKSuriya Kumar

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Overview

Randomized trial finds comparable nicotine dependence reductions from aromatherapy and nicotine replacement therapy in transgender women, suggesting plant-based scents can support cessation.

Key Points

  • To compare the effectiveness of indigenous aromatherapy against nicotine replacement therapy in reducing nicotine dependence among transgender women.
  • A parallel-group randomized controlled trial was conducted in Puducherry among 50 transgender women who were current tobacco users willing to reduce or quit.
  • Participants were randomized 1:1 to receive either indigenous aromatherapy (n=25) or nicotine replacement therapy (n=25), alongside standardized behavioral counseling.
  • Nicotine dependence was measured via the Fagerström Test for Nicotine Dependence (FTND) at baseline, 45 days, and 3 months.
  • Between-group FTND scores did not differ significantly at baseline (5.68 vs. 6.00; p = .216), 45 days (4.88 vs. 5.32; p = .155), or 3 months (4.60 vs. 4.56; p = .958).
  • FTND scores decreased significantly from baseline to 3 months within both the aromatherapy group (p < .001) and the nicotine replacement therapy group (p = .002).

Cite This Study

Sidhu et al. (2026) studied this question.

synapsesocial.com/papers/6a99353a636c6408cfa7d3e4https://doi.org/10.1080/26895269.2026.2725206
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