Key result
Left subclavian valve-in-valve TAVR completely resolves symptoms in a patient with prior modified Bentall repair.
Why the study?
Valve-in-valve TAVR may improve in-hospital outcomes over reoperative SAVR, particularly in patients with elevated surgical risk.
Case Report (n=1)
Trans-subclavian valve-in-valve TAVR can be successfully performed in patients with complex prior aortic surgeries including modified Bentall root replacement and coarctation repair.
Supports feasibility of alternative-access valve-in-valve TAVR in complex aortic disease; hypothesis-generating pending larger studies.
Valve-in-valve transcatheter aortic valve replacement (TAVR) may offer improved in-hospital outcomes compared with reoperative surgical aortic valve replacement (SAVR) and is especially helpful in patients with elevated surgical risk. In this report, we describe a 53-year-old man with history of coarctation, bicuspid aortic valve, and ascending aortic aneurysm who underwent graft repair of his coarctation as well as modified Bentall root replacement, and who presented with acutely worsening chest pain and dyspnea on exertion. Left heart catheterization revealed severe bioprosthetic aortic valve stenosis without significant coronary artery disease. Valve-in-valve TAVR was performed via the left subclavian artery. The patient had complete symptom resolution on follow-up.
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Gasparis et al. (2026) conducted a case report in Severe bioprosthetic aortic valve stenosis (n=1). Valve-in-valve TAVR via the left subclavian artery was evaluated on Symptom resolution. Valve-in-valve TAVR via the left subclavian artery resulted in complete symptom resolution in a 53-year-old man with severe bioprosthetic aortic valve stenosis and previous modified Bentall repair.
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