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September 3, 2026Journal of Computer Assisted Tomography

The Spiderweb Sign: A Pulmonary CT Finding After Intranodal Lymphangiography

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Authors

DLDoyle LangSASadeer AlzubaidiSASayf Al-Katib

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Overview

Retrospective case series reveals a benign pulmonary spiderweb sign on CT scans after lymphangiography, highlighting the importance of avoiding misinterpretation as acute pathology.

Key Points

  • To describe and characterize a distinctive pulmonary CT imaging finding, designated the spiderweb sign, observed in patients following intranodal lymphangiography.
  • Retrospective review of patients who underwent lymphangiograms at a single tertiary care center from January 2022 to December 2025.
  • Identified 11 patients who had thoracic CT imaging performed within 1 week of the lymphangiography procedure.
  • Extracted procedural parameters to assess potential associations with the presence or absence of the spiderweb sign.
  • The spiderweb sign was observed in 4 of 11 patients (36.4%), characterized by hyperdense linear opacities outlining the interlobular septa, peribronchovascular interstitium, and visceral pleura.
  • No definitive associations were identified between specific procedural parameters and the occurrence of the imaging finding.
  • The postprocedural imaging findings appeared clinically benign and followed pulmonary lymphatic pathways without indicating active or developing pulmonary pathology.

Cite This Study

Lang et al. (2026) studied this question.

synapsesocial.com/papers/6a993547636c6408cfa7d73bhttps://doi.org/10.1097/rct.0000000000001920
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