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September 3, 2026Annals of Internal Medicine Clinical CasesOpen Access

Severe Aortic Stenosis and Bilateral Vertebral Artery Stenosis: When “Normal” Blood Pressure Is Not Safe

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Authors

AKAbdullah KılıçTWTallha WaheedSGSamrah Ghani

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Overview

Case report demonstrates successful aortic valve replacement in severe aortic and vertebral artery stenosis, highlighting the need for individualized blood pressure targets.

Key Points

  • To describe the clinical management and hemodynamic considerations in a patient with severe aortic stenosis complicated by bilateral vertebral artery stenosis.
  • Evaluated a 62-year-old woman presenting with recurrent syncope, diplopia, ptosis, and focal weakness using magnetic resonance imaging and hemodynamic assessment.
  • Implemented individualized blood pressure management and multidisciplinary planning ahead of surgical aortic valve replacement.
  • Neurologic symptoms were identified as hemodynamic vertebrobasilar hypoperfusion driven by exhausted cerebrovascular reserve rather than embolic stroke, despite normal systemic blood pressure.
  • Following aortic valve replacement supported by tailored blood pressure targets, the patient experienced complete resolution of syncope and focal neurologic symptoms.

Cite This Study

Kılıç et al. (2026) studied this question.

synapsesocial.com/papers/6a99355b636c6408cfa7d814https://doi.org/10.7326/aimcc.2026.0024
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