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September 3, 2026Sport Sciences for HealthOpen Access

Understanding non-participation in a remote exercise trial among breast cancer survivors undergoing adjuvant endocrine therapy: a cross-sectional survey

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Authors

HBHenrique Ims BortolozoMCMiguel Soares ConceiçãoVPValéria L. G. Panissa

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Overview

Randomized trial uncovers higher preexisting activity among non-participants in breast cancer survivors, suggesting perceived self-sufficiency and in-person testing logistics hinder trial enrollment.

Key Points

  • To identify reasons for non-participation and evaluate clinical and physical profiles of breast cancer survivors on adjuvant endocrine therapy who declined a remote exercise trial.
  • Nested within a randomized trial (ReBEC RBR-3tqb39m), 73 screened breast cancer survivors on adjuvant endocrine therapy were evaluated, of whom 39 enrolled and 30 declined.
  • Surveyed 21 decliners regarding non-participation reasons, physical activity (IPAQ), fatigue (FACT-F), and quality of life (FACT-B), comparing metrics to baseline acceptors (N=39).
  • Decliners reported significantly greater baseline physical activity than acceptors (IPAQ: 3,108 [1,840–5,139] vs. 2,046 [960–4,216] MET-min/week; p = 0.04).
  • Fatigue showed a non-significant trend toward better scores among decliners (FACT-F: 134 vs. 118; p = 0.06), while quality of life did not differ (FACT-B: 113 vs. 110; p = 0.332).
  • The predominant reasons for declining participation were preexisting physical activity (52%) and lack of time for required in-person baseline assessments (48%).

Cite This Study

Bortolozo et al. (2026) studied this question.

synapsesocial.com/papers/6a9935a0636c6408cfa7dff3https://doi.org/10.1007/s11332-026-01924-1
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